Academy Award-winning actress Rachel Weisz will star in the upcoming series Dead Ringers, marking Weisz's first television role. Amazon Studios and Annapurna Television are co-producing the series, inspired by the 1988 thriller. Alice Birch will write and executive produce. Dead Ringers will be available exclusively on Prime Video in more than 200 countries and territories worldwide.

In a modern take on David Cronenberg's thriller starring Jeremy Irons, the series will feature Weisz playing the double lead role of the Mantle twins, who share everything: drugs, lovers, and an unapologetic desire to do whatever it takes, including pushing the boundaries on medical ethics in an effort to challenge antiquated practices and bring women's healthcare to the forefront.